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Overexpression of TET dioxygenases in seminomas associates with low levels of DNA methylation and hydroxymethylation
Germ cell tumors and particularly seminomas reflect the epigenomic features of their parental primordial germ cells, including the genomic DNA hypomethylation and expression of pluripotent cell markers. Because the DNA hypomethylation might be a result of TET dioxygenase activity, we examined expres...
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| Publicado no: | Mol Carcinog |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5503132/ https://ncbi.nlm.nih.gov/pubmed/28218476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22638 |
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