Overexpression of TET dioxygenases in seminomas associates with low levels of DNA methylation and hydroxymethylation

Germ cell tumors and particularly seminomas reflect the epigenomic features of their parental primordial germ cells, including the genomic DNA hypomethylation and expression of pluripotent cell markers. Because the DNA hypomethylation might be a result of TET dioxygenase activity, we examined expres...

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Publicat a:Mol Carcinog
Autors principals: Benešová, Martina, Trejbalová, Kateřina, Kučerová, Dana, Vernerová, Zdenka, Hron, Tomáš, Szabó, Arpád, Amouroux, Rachel, Klézl, Petr, Hajkova, Petra, Hejnar, Jiří
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503132/
https://ncbi.nlm.nih.gov/pubmed/28218476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22638
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