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Suppressive IL-17A(+)Foxp3(+) and ex-Th17 IL-17A(neg)Foxp3(+) T(reg) cells are a source of tumour-associated T(reg) cells
Th17 and regulatory T (T(reg)) cells are integral in maintaining immune homeostasis and Th17–T(reg) imbalance is associated with inflammatory immunosuppression in cancer. Here we show that Th17 cells are a source of tumour-induced Foxp3(+) cells. In addition to natural (n)T(reg) and induced (i)T(reg...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355894/ https://ncbi.nlm.nih.gov/pubmed/28290453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14649 |
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