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TLR4 regulates IFN-γ and IL-17 production by both thymic and induced Foxp3(+) T(regs) during intestinal inflammation
T(regs) play a crucial role in the maintenance of intestinal immune homeostasis. However, significant numbers of Foxp3(+) T(regs) accumulate in the inflamed lesions in experimental colitis and in IBD patients. T(reg) production of the proinflammatory cytokines IFN-γ and/or IL-17 may arguably explain...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Leukocyte Biology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197555/ https://ncbi.nlm.nih.gov/pubmed/25015957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0114-056RR |
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