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IL-12 Converts Foxp3(+) Regulatory T Cells to Foxp3(+)IFN-γ(+) T Cells with Inhibitory Functions During Induction of Colitis
Regulatory T (Treg) cells are plastic, but the in vivo mechanisms by which they are converted into Foxp3(+)interferon (IFN)-γ(+) T cells, and whether these converted cells retain the ability to inhibit colitis, are not clear. METHODS: Foxp3(+) Treg cells were generated by culture of naïve CD4(+) T c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109200/ https://ncbi.nlm.nih.gov/pubmed/21419767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.03.009 |
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