CpG Oligodeoxynucleotide Inhibits Cockroach-Induced Asthma via Induction of IFN-γ(+) Th1 Cells or Foxp3(+) Regulatory T Cells in the Lung

PURPOSE: CpG oligodeoxynucleotide (CpG-ODN), a TLR9 agonist, activates innate immunity and induces Th1 response. Although the immune modulatory effect of CpG-ODN has been extensively studied, its function in cockroach extract-induced allergic asthma has not been studied. Here, we investigated the in...

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Detalhes bibliográficos
Publicado no:Allergy Asthma Immunol Res
Main Authors: Kim, Do-Hyun, Sohn, Jung-Ho, Park, Hong-Jai, Lee, Jae-Hyun, Park, Jung-Won, Choi, Je-Min
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773215/
https://ncbi.nlm.nih.gov/pubmed/26922937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2016.8.3.264
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