Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

Various signaling pathways exert critical roles in the epithelial to mesenchymal transition (EMT) and cancer stem cells (CSCs). The Wnt/beta-catenin, PI3K/PTEN/Akt/mTORC, Ras/Raf/MEK/ERK, hedgehog (Hh), Notch and TP53 pathways elicit essential regulatory influences on cancer initiation, EMT and prog...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: McCubrey, James A., Fitzgerald, Timothy L., Yang, Li V., Lertpiriyapong, Kvin, Steelman, Linda S., Abrams, Stephen L., Montalto, Giuseppe, Cervello, Melchiorre, Neri, Luca M., Cocco, Lucio, Martelli, Alberto M., Laidler, Piotr, Dulińska-Litewka, Joanna, Rakus, Dariusz, Gizak, Agnieszka, Nicoletti, Ferdinando, Falzone, Luca, Candido, Saverio, Libra, Massimo
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355173/
https://ncbi.nlm.nih.gov/pubmed/27999207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13991
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