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Sensitization of glycoengineered interferon-β1a-resistant cancer cells by cFLIP inhibition for enhanced anti-cancer therapy

In this study, we examined the molecular mechanism underlying the resistance of cancer cells to R27T, a glycoengineered version of recombinant human interferon (IFN)-β1a, and sought to overcome R27T resistance through combination therapy. R27T has been shown to induce anti-proliferation and apoptosi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Tae-Eun, Hong, Sungyoul, Song, Kyoung, Park, Sang-Ho, Shin, Young Kee
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355153/
https://ncbi.nlm.nih.gov/pubmed/28086218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14573
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