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Structure-based glycoengineering of interferon lambda 4 enhances its productivity and anti-viral potency
Interferon lambda 4 (IFNλ4) has been recently known and studied for its role in hepatitis C virus (HCV) infection, but its clinical potential is significantly hampered due to its poor expression in vitro. Our study reports the successful production of IFNλ4 from a mammalian cell line through a glyco...
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| Veröffentlicht in: | Cytokine |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier Ltd.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7129780/ https://ncbi.nlm.nih.gov/pubmed/31479875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2019.154833 |
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