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Metformin promotes apoptosis in hepatocellular carcinoma through the CEBPD-induced autophagy pathway
Metformin, as an AMP-activated protein kinase (AMPK) activator, can activate autophagy. A study showed that metformin decreased the risk of hepatocellular carcinoma (HCC) in diabetic patients. However, the detailed mechanism in the metformin-mediated anticancer effect remains an open question. Trans...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355142/ https://ncbi.nlm.nih.gov/pubmed/28099155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14640 |
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