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Metformin Promotes Apoptosis but Suppresses Autophagy in Glucose-Deprived H4IIE Hepatocellular Carcinoma Cells

BACKGROUND: Metformin, a well-known anti-diabetic drug, has gained interest due to its association with the reduction of the prevalence of cancer in patients with type 2 diabetes and the anti-proliferative effect of metformin in several cancer cells. Here, we investigated the anti-proliferative effe...

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Bibliografische gegevens
Gepubliceerd in:Diabetes Metab J
Hoofdauteur: Park, Deok-Bae
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Korean Diabetes Association 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696989/
https://ncbi.nlm.nih.gov/pubmed/26706918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2015.39.6.518
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