Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation

Despite the activation of autophagy may enable residual cancer cells to survive and allow tumor relapse, excessive activation of autophagy may eventually lead to cell death. However, the details of the association of autophagy with primary resistance in hepatocellular carcinoma (HCC) remain less cle...

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Bibliografski detalji
Izdano u:Front Cell Dev Biol
Glavni autori: Lai, Hong-Yue, Tsai, Hsin-Hwa, Yen, Chia-Jui, Hung, Liang-Yi, Yang, Ching-Chieh, Ho, Chung-Han, Liang, Hsin-Yin, Chen, Feng-Wei, Li, Chien-Feng, Wang, Ju-Ming
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Cell and Developmental Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931828/
https://ncbi.nlm.nih.gov/pubmed/33681180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.596655
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