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Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation

Despite the activation of autophagy may enable residual cancer cells to survive and allow tumor relapse, excessive activation of autophagy may eventually lead to cell death. However, the details of the association of autophagy with primary resistance in hepatocellular carcinoma (HCC) remain less cle...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Lai, Hong-Yue, Tsai, Hsin-Hwa, Yen, Chia-Jui, Hung, Liang-Yi, Yang, Ching-Chieh, Ho, Chung-Han, Liang, Hsin-Yin, Chen, Feng-Wei, Li, Chien-Feng, Wang, Ju-Ming
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931828/
https://ncbi.nlm.nih.gov/pubmed/33681180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.596655
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