Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation

Despite the activation of autophagy may enable residual cancer cells to survive and allow tumor relapse, excessive activation of autophagy may eventually lead to cell death. However, the details of the association of autophagy with primary resistance in hepatocellular carcinoma (HCC) remain less cle...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Dev Biol
Hoofdauteurs: Lai, Hong-Yue, Tsai, Hsin-Hwa, Yen, Chia-Jui, Hung, Liang-Yi, Yang, Ching-Chieh, Ho, Chung-Han, Liang, Hsin-Yin, Chen, Feng-Wei, Li, Chien-Feng, Wang, Ju-Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Cell and Developmental Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931828/
https://ncbi.nlm.nih.gov/pubmed/33681180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.596655
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