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Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation

Despite the activation of autophagy may enable residual cancer cells to survive and allow tumor relapse, excessive activation of autophagy may eventually lead to cell death. However, the details of the association of autophagy with primary resistance in hepatocellular carcinoma (HCC) remain less cle...

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Podrobná bibliografie
Vydáno v:Front Cell Dev Biol
Hlavní autoři: Lai, Hong-Yue, Tsai, Hsin-Hwa, Yen, Chia-Jui, Hung, Liang-Yi, Yang, Ching-Chieh, Ho, Chung-Han, Liang, Hsin-Yin, Chen, Feng-Wei, Li, Chien-Feng, Wang, Ju-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931828/
https://ncbi.nlm.nih.gov/pubmed/33681180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.596655
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