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Amplification of ACK1 promotes gastric tumorigenesis via ECD-dependent p53 ubiquitination degradation
Amplification or over-expression of an activated Cdc42-associated kinase 1 (ACK1) gene is common in breast, lung and ovarian cancers. However, little is known about the role of ACK1 in gastric tumorigenesis. Here, we found that DNA copy numbers of the ACK1 gene and its mRNA expression levels were si...
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| I publikationen: | Oncotarget |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Impact Journals LLC
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355047/ https://ncbi.nlm.nih.gov/pubmed/26498357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6194 |
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