ECD promotes gastric cancer metastasis by blocking E3 ligase ZFP91-mediated hnRNP F ubiquitination and degradation

The human ortholog of the Drosophila ecdysoneless gene (ECD) is required for embryonic development and cell-cycle progression; however, its role in cancer progression and metastasis remains unclear. Here, we found that ECD is frequently overexpressed in gastric cancer (GC), especially in metastatic...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Xu, Song-Hui, Zhu, Song, Wang, Yanjie, Huang, Jin-Zhou, Chen, Min, Wu, Qing-Xia, He, Yu-Tian, Chen, De, Yan, Guang-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924763/
https://ncbi.nlm.nih.gov/pubmed/29706618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0525-x
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