Spleen cells from young but not old immunized mice eradicate large established cancers

PURPOSE: Solid tumors that have grown two weeks or longer in mice and have diameters larger than 1 cm are histologically indistinguishable from autochthonous human cancers. When experimental tumors reach this clinically relevant size, they are usually refractory to most immunotherapies but may be de...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Schreiber, Karin, Arina, Ainhoa, Engels, Boris, Spiotto, Michael T., Sidney, John, Sette, Alessandro, Karrison, Theodore, Weichselbaum, Ralph R., Rowley, Donald A., Schreiber, Hans
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354938/
https://ncbi.nlm.nih.gov/pubmed/22415314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0127
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