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Transfer of allogeneic CD4(+) T cells rescues CD8(+) T cells in anti-PD-L1–resistant tumors leading to tumor eradication

Adoptively transferred CD8(+) T cells can stabilize the size of solid tumors over long periods of time by exclusively recognizing antigen cross-presented on tumor stroma. However, these tumors eventually escape T cell–mediated growth control. The aim of this study was to eradicate such persistent ca...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Arina, Ainhoa, Karrison, Theodore, Galka, Eva, Schreiber, Karin, Weichselbaum, Ralph R., Schreiber, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354300/
https://ncbi.nlm.nih.gov/pubmed/28077434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0293
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