Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer

Clinical studies in breast cancer suggest important associations between intratumoral hypoxia, the upregulation of epidermal growth factor receptor (EGFR or HER1), hypoxia-inducible factor 1α (HIF-1α), and reduced patient survival. However, direct molecular links between EGFR and the hypoxia signali...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kozlova, Nina, Wottawa, Marieke, Katschinski, Dörthe Magdalena, Kristiansen, Glen, Kietzmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354778/
https://ncbi.nlm.nih.gov/pubmed/28038470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14241
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