Sequence Determinants in Hypoxia-inducible Factor-1α for Hydroxylation by the Prolyl Hydroxylases PHD1, PHD2, and PHD3

Hypoxia-inducible factor (HIF) is a heterodimeric transcription factor induced by hypoxia. Under normoxic conditions, site-specific proline hydroxylation of the α subunits of HIF allows recognition by the von Hippel-Lindau tumor suppressor protein (VHL), a component of an E3 ubiquitin ligase complex...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Huang, Jianhe, Zhao, Quan, Mooney, Sharon M., Lee, Frank S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828037/
https://ncbi.nlm.nih.gov/pubmed/12181324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M206955200
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky