טוען...
Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation
Small molecule inhibitors of pre-mRNA splicing are important tools for identifying new spliceosome assembly intermediates, allowing a finer dissection of spliceosome dynamics and function. Here, we identified a small molecule that inhibits human pre-mRNA splicing at an intermediate stage during conv...
שמור ב:
| הוצא לאור ב: | eLife |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354520/ https://ncbi.nlm.nih.gov/pubmed/28300534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23533 |
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