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Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system
In this study, the CRISPR/Cas9 technology was used to establish murine tumor cell lines, devoid of MHC I or MHC II surface expression, respectively. The melanoma cell line B16F10 and the murine breast cancer cell line EO-771, the latter stably expressing the tumor antigen NY-BR-1 (EO-NY), were trans...
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| 發表在: | PLoS One |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354463/ https://ncbi.nlm.nih.gov/pubmed/28301575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174077 |
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