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Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies

BACKGROUND: Transcriptional reprogramming is a fundamental process of living cells in order to adapt to environmental and endogenous cues. In order to allow flexible and timely control over gene expression without the interference of native gene expression machinery, a large number of studies have f...

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Bibliografiske detaljer
Udgivet i:Microb Cell Fact
Main Authors: Jensen, Emil D., Ferreira, Raphael, Jakočiūnas, Tadas, Arsovska, Dushica, Zhang, Jie, Ding, Ling, Smith, Justin D., David, Florian, Nielsen, Jens, Jensen, Michael K., Keasling, Jay D.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353793/
https://ncbi.nlm.nih.gov/pubmed/28298224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0664-2
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