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Glycine as a d-amino acid surrogate in the K(+)-selectivity filter

The K+ channel-selectivity filter consists of two absolutely conserved glycine residues. Crystal structures show that the first glycine in the selectivity filter, Gly-77 in KcsA, is in a left-handed helical conformation. Although the left-handed helical conformation is not favorable for the naturall...

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Hlavní autoři: Valiyaveetil, Francis I., Sekedat, Matthew, MacKinnon, Roderick, Muir, Tom W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC535378/
https://ncbi.nlm.nih.gov/pubmed/15563591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407820101
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