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Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

Superoxide dismutase reduces injury in many disease processes, implicating superoxide anion radical (O2-.) as a toxic species in vivo. A critical target of superoxide may be nitric oxide (NO.) produced by endothelium, macrophages, neutrophils, and brain synaptosomes. Superoxide and NO. are known to...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Beckman, J S, Beckman, T W, Chen, J, Marshall, P A, Freeman, B A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1990
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2154753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1620
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