Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin

Multidrug resistance(MDR) is a major obstacle to efficiency of breast cancer chemotherapy. We investigated whether combination of metformin and 2-deoxyglucose reverses MDR of MCF-7/Dox cells and tried to elucidate the possible mechanisms. The combination of metformin and 2-deoxyglucose selectively e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Xue, Chaojun, Wang, Changyuan, Sun, Yaoting, Meng, Qiang, Liu, Zhihao, Huo, Xiaokui, Sun, Pengyuan, Sun, Huijun, Ma, Xiaodong, Ma, Xiaochi, Peng, Jinyong, Liu, Kexin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352427/
https://ncbi.nlm.nih.gov/pubmed/28052008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14373
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak