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CBX7 suppresses cell proliferation, migration, and invasion through the inhibition of PTEN/Akt signaling in pancreatic cancer

Chromobox protein homolog 7 (CBX7), one of the polycomb group (PcG) proteins, is a transcriptional repressor involved in the regulation of cell proliferation and senescence. In the present study, we showed that CBX7 negatively regulates the proliferation, viability, chemoresistance, and migration of...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Ni, Sujie, Wang, Hongwei, Zhu, Xiaolin, Wan, Chunhua, Xu, Junfei, Lu, Chen, Xiao, Li, He, Jiaqi, Jiang, Chongyi, Wang, Wei, He, Zhixian
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352378/
https://ncbi.nlm.nih.gov/pubmed/28030829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14037
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