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Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway

Pancreatic stellate cells (PSCs) are important components of the tumor microenvironment in pancreatic cancer (PC) and contribute to its development and metastasis through mechanisms that remain incompletely characterized. Tumor hypoxia affects the function and behavior of PC and stromal cells, and c...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Cao, Wenpeng, Zeng, Zhirui, He, Zhiwei, Lei, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993707/
https://ncbi.nlm.nih.gov/pubmed/33653966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202569
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