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Upregulation of PREX2 promotes the proliferation and migration of hepatocellular carcinoma cells via PTEN-AKT signaling

Phosphatidylinositol-3,4,5-trisphosphate Rac exchanger 2 (PREX2), a regulator of the small guanosine triphosphatase Rac, demonstrates an inhibitory effect on the activity of phosphatase and tensin homolog (PTEN). Previously, PREX2 was implicated in the regulation of cell invasion in hepatocellular c...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: HE, SHUJIE, LIN, JUAN, YU, SHAOPING, SUN, SHIJIE
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774577/
https://ncbi.nlm.nih.gov/pubmed/26998152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4164
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