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Upregulation of PREX2 promotes the proliferation and migration of hepatocellular carcinoma cells via PTEN-AKT signaling

Phosphatidylinositol-3,4,5-trisphosphate Rac exchanger 2 (PREX2), a regulator of the small guanosine triphosphatase Rac, demonstrates an inhibitory effect on the activity of phosphatase and tensin homolog (PTEN). Previously, PREX2 was implicated in the regulation of cell invasion in hepatocellular c...

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Publicat a:Oncol Lett
Autors principals: HE, SHUJIE, LIN, JUAN, YU, SHAOPING, SUN, SHIJIE
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774577/
https://ncbi.nlm.nih.gov/pubmed/26998152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4164
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