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Upregulation of PREX2 promotes the proliferation and migration of hepatocellular carcinoma cells via PTEN-AKT signaling

Phosphatidylinositol-3,4,5-trisphosphate Rac exchanger 2 (PREX2), a regulator of the small guanosine triphosphatase Rac, demonstrates an inhibitory effect on the activity of phosphatase and tensin homolog (PTEN). Previously, PREX2 was implicated in the regulation of cell invasion in hepatocellular c...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: HE, SHUJIE, LIN, JUAN, YU, SHAOPING, SUN, SHIJIE
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774577/
https://ncbi.nlm.nih.gov/pubmed/26998152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4164
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