A carregar...
Prospective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells
Inhibition of the HSP90 chaperone results in depletion of many signaling proteins that drive tumorigenesis, such as downstream effectors of KRAS, the most commonly mutated human oncogene. As a consequence, several small-molecule HSP90 inhibitors are being evaluated in clinical trials as anticancer a...
Na minha lista:
| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352352/ https://ncbi.nlm.nih.gov/pubmed/28032595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13841 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|