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The immunomodulatory effects of TNF-α inhibitors on human Th17 cells via RORγt histone acetylation
The presence of interleukin (IL)-17-related cytokines correlates with rheumatoid arthritis (RA) pathogenesis. Epigenetic modifications, including histone acetylation, regulate gene expression in RA pathogenesis. Tumour necrosis factor-alpha (TNF-α) inhibitors such as etanercept and adalimumab, repre...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352343/ https://ncbi.nlm.nih.gov/pubmed/27926504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13791 |
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