The ISG15-specific protease USP18 regulates stability of PTEN

The ubiquitin-like modifier interferon-stimulated gene 15 (ISG15) is implicated in both oncogenic and tumor suppressive programs. Yet, few ISGylation substrates are known and functionally validated in cancer biology. We previously found specific oncoproteins were substrates of ISGylation and were st...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Mustachio, Lisa Maria, Kawakami, Masanori, Lu, Yun, Rodriguez-Canales, Jaime, Mino, Barbara, Behrens, Carmen, Wistuba, Ignacio, Bota-Rabassedas, Neus, Yu, Jun, Lee, J. Jack, Roszik, Jason, Zheng, Lin, Liu, Xi, Freemantle, Sarah J., Dmitrovsky, Ethan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
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Priority Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352120/
https://ncbi.nlm.nih.gov/pubmed/27980214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13914
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