The ISG15-specific protease USP18 regulates stability of PTEN

The ubiquitin-like modifier interferon-stimulated gene 15 (ISG15) is implicated in both oncogenic and tumor suppressive programs. Yet, few ISGylation substrates are known and functionally validated in cancer biology. We previously found specific oncoproteins were substrates of ISGylation and were st...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mustachio, Lisa Maria, Kawakami, Masanori, Lu, Yun, Rodriguez-Canales, Jaime, Mino, Barbara, Behrens, Carmen, Wistuba, Ignacio, Bota-Rabassedas, Neus, Yu, Jun, Lee, J. Jack, Roszik, Jason, Zheng, Lin, Liu, Xi, Freemantle, Sarah J., Dmitrovsky, Ethan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352120/
https://ncbi.nlm.nih.gov/pubmed/27980214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13914
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