The ISG15-specific protease USP18 regulates stability of PTEN

The ubiquitin-like modifier interferon-stimulated gene 15 (ISG15) is implicated in both oncogenic and tumor suppressive programs. Yet, few ISGylation substrates are known and functionally validated in cancer biology. We previously found specific oncoproteins were substrates of ISGylation and were st...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Mustachio, Lisa Maria, Kawakami, Masanori, Lu, Yun, Rodriguez-Canales, Jaime, Mino, Barbara, Behrens, Carmen, Wistuba, Ignacio, Bota-Rabassedas, Neus, Yu, Jun, Lee, J. Jack, Roszik, Jason, Zheng, Lin, Liu, Xi, Freemantle, Sarah J., Dmitrovsky, Ethan
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Priority Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352120/
https://ncbi.nlm.nih.gov/pubmed/27980214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13914
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