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Preclinical evaluation of the PARP inhibitor BMN-673 for the treatment of ovarian clear cell cancer
PURPOSE: To determine if models of ovarian clear cell carcinomas (OCCCs) harbouring defects in homologous recombination (HR) DNA repair of double strand breaks (DSBs) are sensitive to cisplatin and/or PARP inhibition. EXPERIMENTAL DESIGN: The HR status of 12 OCCC cell lines was determined using RAD5...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5351612/ https://ncbi.nlm.nih.gov/pubmed/28002809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14011 |
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