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A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer

The DNA mismatch repair (MMR) system corrects DNA replication mismatches thereby contributing to the maintenance of genomic stability. MMR deficiency has been observed in prostate cancer but its impact on the genomic landscape of these tumours is not known. In order to identify MMR associated mutati...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Alves, Inês Teles, Cano, David, Böttcher, René, van der Korput, Hetty, Dinjens, Winand, Jenster, Guido, Trapman, Jan
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351611/
https://ncbi.nlm.nih.gov/pubmed/27907910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13464
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