Evaluation of a new panel of six mononucleotide repeat markers for the detection of DNA mismatch repair-deficient tumours

BACKGROUND: Microsatellite instability (MSI) is a molecular phenotype due to defective DNA mismatch repair (MMR) system. It is used to predict outcome of colorectal tumours and to screen tumours for Lynch syndrome (LS). A pentaplex panel composed of five mononucleotide markers has been largely recom...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pagin, A, Zerimech, F, Leclerc, J, Wacrenier, A, Lejeune, S, Descarpentries, C, Escande, F, Porchet, N, Buisine, M-P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2013
Gaiak:
Molecular Diagnostics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670492/
https://ncbi.nlm.nih.gov/pubmed/23652311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.213
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