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IκB-α: At the crossroad between oncogenic and tumor-suppressive signals

Nuclear factor κB (NF-κB) is an essential component of tumorigenesis and resistance to cancer treatments. NFKB inhibitor α (IκB-α) acts as a negative regulator of the classical NF-κB pathway through its ability to maintain the presence of NF-κB in the cytoplasm. However, IκB-α is also able to form a...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Morotti, Alessandro, Crivellaro, Sabrina, Panuzzo, Cristina, Carrà, Giovanna, Guerrasio, Angelo, Saglio, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351326/
https://ncbi.nlm.nih.gov/pubmed/28356925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5465
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