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Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex
TP53 is one of the most frequently-mutated and deleted tumor suppressors in cancer, with a dramatic correlation with dismal prognoses. In addition to genetic inactivation, the p53 protein can be functionally inactivated in cancer, through post-transductional modifications, changes in cellular compar...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5187797/ https://ncbi.nlm.nih.gov/pubmed/27916821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17121997 |
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