Identification of Biomarkers in Human Head and Neck Tumor Cell Lines That Predict For In Vitro Sensitivity to Gefitinib

Potential biomarkers were identified for in vitro sensitivity to the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib in head and neck cancer. Gefitinib sensitivity was determined in cell lines, followed by transcript profiling coupled with a novel pathway analysis approac...

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Publicat a:Clin Transl Sci
Autors principals: Hickinson, D. Mark, Marshall, Gayle B., Beran, Garry J., Varella‐Garcia, Marileila, Mills, Elizabeth A., South, Marie C., Cassidy, Andrew M., Acheson, Kerry L, McWalter, Gael, McCormack, Rose M., Bunn, Paul A., French, Tim, Graham, Alex, Holloway, Brian R., Hirsch, Fred R., Speake, Georgina
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2009
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350732/
https://ncbi.nlm.nih.gov/pubmed/20443891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00099.x
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