Identification of Biomarkers in Human Head and Neck Tumor Cell Lines That Predict For In Vitro Sensitivity to Gefitinib

Potential biomarkers were identified for in vitro sensitivity to the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib in head and neck cancer. Gefitinib sensitivity was determined in cell lines, followed by transcript profiling coupled with a novel pathway analysis approac...

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Bibliographic Details
Published in:Clin Transl Sci
Main Authors: Hickinson, D. Mark, Marshall, Gayle B., Beran, Garry J., Varella‐Garcia, Marileila, Mills, Elizabeth A., South, Marie C., Cassidy, Andrew M., Acheson, Kerry L, McWalter, Gael, McCormack, Rose M., Bunn, Paul A., French, Tim, Graham, Alex, Holloway, Brian R., Hirsch, Fred R., Speake, Georgina
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Inc 2009
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350732/
https://ncbi.nlm.nih.gov/pubmed/20443891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00099.x
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