Identification of Biomarkers in Human Head and Neck Tumor Cell Lines That Predict For In Vitro Sensitivity to Gefitinib

Potential biomarkers were identified for in vitro sensitivity to the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib in head and neck cancer. Gefitinib sensitivity was determined in cell lines, followed by transcript profiling coupled with a novel pathway analysis approac...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Hickinson, D. Mark, Marshall, Gayle B., Beran, Garry J., Varella‐Garcia, Marileila, Mills, Elizabeth A., South, Marie C., Cassidy, Andrew M., Acheson, Kerry L, McWalter, Gael, McCormack, Rose M., Bunn, Paul A., French, Tim, Graham, Alex, Holloway, Brian R., Hirsch, Fred R., Speake, Georgina
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350732/
https://ncbi.nlm.nih.gov/pubmed/20443891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00099.x
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