Identification of Biomarkers in Human Head and Neck Tumor Cell Lines That Predict For In Vitro Sensitivity to Gefitinib

Potential biomarkers were identified for in vitro sensitivity to the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib in head and neck cancer. Gefitinib sensitivity was determined in cell lines, followed by transcript profiling coupled with a novel pathway analysis approac...

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Bibliografiska uppgifter
I publikationen:Clin Transl Sci
Huvudupphovsmän: Hickinson, D. Mark, Marshall, Gayle B., Beran, Garry J., Varella‐Garcia, Marileila, Mills, Elizabeth A., South, Marie C., Cassidy, Andrew M., Acheson, Kerry L, McWalter, Gael, McCormack, Rose M., Bunn, Paul A., French, Tim, Graham, Alex, Holloway, Brian R., Hirsch, Fred R., Speake, Georgina
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Inc 2009
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350732/
https://ncbi.nlm.nih.gov/pubmed/20443891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00099.x
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