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Bitransgenesis with β(2)‐Adrenergic Receptors or Adenylyl Cyclase Fails to Improve β(1)‐Adrenergic Receptor Cardiomyopathy
Cardiomyopathic effects of β‐adrenergic receptor (βAR) signaling are primarily due to the β(1)AR subtype. β(1)/β(2)AR and β(1)/adenylyl cyclase type 5 (AC5) bitransgenic mice were created to test the hypothesis that β(2)AR or AC5 co‐overexpression has beneficial effects in β(1)AR‐mediated cardiomyop...
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| Izdano u: | Clin Transl Sci |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Publishing Inc
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350669/ https://ncbi.nlm.nih.gov/pubmed/20443853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00061.x |
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