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Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88
Toll-like receptors (TLRs) such as TLR2 and TLR4 have been implicated in host response to mycobacterial infection. Here, mice deficient in the TLR adaptor molecule myeloid differentiation factor 88 (MyD88) were infected with Mycobacterium tuberculosis (MTB). While primary MyD88(–/–) macrophages and...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535064/ https://ncbi.nlm.nih.gov/pubmed/15599404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421027 |
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