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Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88

Toll-like receptors (TLRs) such as TLR2 and TLR4 have been implicated in host response to mycobacterial infection. Here, mice deficient in the TLR adaptor molecule myeloid differentiation factor 88 (MyD88) were infected with Mycobacterium tuberculosis (MTB). While primary MyD88(–/–) macrophages and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fremond, Cecile M., Yeremeev, Vladimir, Nicolle, Delphine M., Jacobs, Muazzam, Quesniaux, Valerie F., Ryffel, Bernhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC535064/
https://ncbi.nlm.nih.gov/pubmed/15599404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421027
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