Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells

Atopic dermatitis (AD) is a chronic Th2 type inflammatory skin disorder. Here we report that MyD88 signaling is crucial in the pathogenesis of experimental AD induced by vitamin D3 analog MC903. The clinical signs and inflammation caused by MC903 are drastically reduced in MyD88(−/−) mice with dimin...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Li, Changwei, Maillet, Isabelle, Mackowiak, Claire, Viala, Camille, Di Padova, Franco, Li, Mei, Togbe, Dieudonnée, Quesniaux, Valérie, Lai, Yuping, Ryffel, Bernhard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477596/
https://ncbi.nlm.nih.gov/pubmed/28383552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.90
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