Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells

Atopic dermatitis (AD) is a chronic Th2 type inflammatory skin disorder. Here we report that MyD88 signaling is crucial in the pathogenesis of experimental AD induced by vitamin D3 analog MC903. The clinical signs and inflammation caused by MC903 are drastically reduced in MyD88(−/−) mice with dimin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Li, Changwei, Maillet, Isabelle, Mackowiak, Claire, Viala, Camille, Di Padova, Franco, Li, Mei, Togbe, Dieudonnée, Quesniaux, Valérie, Lai, Yuping, Ryffel, Bernhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477596/
https://ncbi.nlm.nih.gov/pubmed/28383552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.90
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