Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells

Atopic dermatitis (AD) is a chronic Th2 type inflammatory skin disorder. Here we report that MyD88 signaling is crucial in the pathogenesis of experimental AD induced by vitamin D3 analog MC903. The clinical signs and inflammation caused by MC903 are drastically reduced in MyD88(−/−) mice with dimin...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Li, Changwei, Maillet, Isabelle, Mackowiak, Claire, Viala, Camille, Di Padova, Franco, Li, Mei, Togbe, Dieudonnée, Quesniaux, Valérie, Lai, Yuping, Ryffel, Bernhard
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477596/
https://ncbi.nlm.nih.gov/pubmed/28383552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.90
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