Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells

Atopic dermatitis (AD) is a chronic Th2 type inflammatory skin disorder. Here we report that MyD88 signaling is crucial in the pathogenesis of experimental AD induced by vitamin D3 analog MC903. The clinical signs and inflammation caused by MC903 are drastically reduced in MyD88(−/−) mice with dimin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Li, Changwei, Maillet, Isabelle, Mackowiak, Claire, Viala, Camille, Di Padova, Franco, Li, Mei, Togbe, Dieudonnée, Quesniaux, Valérie, Lai, Yuping, Ryffel, Bernhard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477596/
https://ncbi.nlm.nih.gov/pubmed/28383552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.90
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