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Hsp70 displaces small heat shock proteins from aggregates to initiate protein refolding
Small heat shock proteins (sHsps) are an evolutionary conserved class of ATP‐independent chaperones that protect cells against proteotoxic stress. sHsps form assemblies with aggregation‐prone misfolded proteins, which facilitates subsequent substrate solubilization and refolding by ATP‐dependent Hsp...
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| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350560/ https://ncbi.nlm.nih.gov/pubmed/28219929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593378 |
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