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Long-term biased β-arrestin signaling improves cardiac structure and function in dilated cardiomyopathy

BACKGROUND: Biased agonism of the angiotensin receptor (AT1R) is known to promote cardiac contractility. Our laboratory indicated that these effects may be due to changes at the level of the myofilaments. However, these signaling mechanisms remain unknown. As a common finding in dilated cardiomyopat...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Ryba, David M., Li, Jieli, Cowan, Conrad L., Russell, Brenda, Wolska, Beata M., Solaro, R. John
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350031/
https://ncbi.nlm.nih.gov/pubmed/28104714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.024482
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