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Long-term biased β-arrestin signaling improves cardiac structure and function in dilated cardiomyopathy

BACKGROUND: Biased agonism of the angiotensin receptor (AT1R) is known to promote cardiac contractility. Our laboratory indicated that these effects may be due to changes at the level of the myofilaments. However, these signaling mechanisms remain unknown. As a common finding in dilated cardiomyopat...

詳細記述

保存先:
書誌詳細
出版年:Circulation
主要な著者: Ryba, David M., Li, Jieli, Cowan, Conrad L., Russell, Brenda, Wolska, Beata M., Solaro, R. John
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350031/
https://ncbi.nlm.nih.gov/pubmed/28104714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.024482
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