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The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition
Colorectal cancer (CRC) is a leading cause of cancer-related death throughout the world. Despite improved screening efforts, most CRCs are diagnosed at late stages when surgery alone is not curative. Moreover, the low 5-year survival rate (∼8-13%) for those living with stage IV CRC highlights the ne...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5349998/ https://ncbi.nlm.nih.gov/pubmed/27902462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13654 |
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