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Toxoplasma gondii inhibits cytochrome c-induced caspase activation in its host cell by interference with holo-apoptosome assembly

Inhibition of programmed cell death pathways of mammalian cells often facilitates the sustained survival of intracellular microorganisms. The apicomplexan parasite Toxoplasma gondii is a master regulator of host cell apoptotic pathways. Here, we have characterized a novel anti-apoptotic activity of...

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Bibliografiske detaljer
Udgivet i:Microb Cell
Main Authors: Graumann, Kristin, Schaumburg, Frieder, Reubold, Thomas F., Hippe, Diana, Eschenburg, Susanne, Lüder, Carsten G. K.
Format: Artigo
Sprog:Inglês
Udgivet: Shared Science Publishers OG 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349237/
https://ncbi.nlm.nih.gov/pubmed/28357287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2015.05.201
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